Programme

• Sun
• Mon
• Tue
• Wed
• Thu
• Fri
• Sat

• Sunday, 3 April

  17:00-18:00	Arrival and registration
  18:00	Welcome ceremony Introduction to the school, general information, and assignment of students to Agora teams
  19:00	Welcome drinks followed by buffet dinner

• Monday, 4 April

  9:00-9:45	Richard Robitaille (Université de Montréal • Montreal, QC, Canada) Decoding the code: beyond the measurements of Ca2+ in glial cells [30 min + 10 min discussion]
  9:45-10:30	Alfonso Araque (University of Minnesota • Minneapolis, MN, USA) Stimulating neurons and astrocytes [30 min + 10 min discussion]
  10:30-10:50	Coffee break
  10:50-11:35	Amit Agarwal (Heidelberg University • Heidelberg, Germany) CaSCaDe - Analysis of Ca2+ signals in glial cells [30 min + 10 min discussion]
  11:35-12:10	Student presentations [7 min + 3 min discussion each] Bonnie Plug (Amsterdam, The Netherlands) Heterogeneity of astrocytes in vanishing white matter disease: central in white matter lesion repair? Maria João Pereira (Leuven, Belgium) The contribution of astrocytes subtypes in adult brain plasticity Darren Clarke (Montreal, Canada) Glial heterogeneity at inhibitory hippocampal synapses
  12:10-12:30	Agora • Preparation (1)
  12:30-14:00	Lunch
  14:00-15:05	Student presentations [7 min + 3 min discussion each] Quinty Bisseling (Amsterdam, The Netherlands) The role of MLC1, volume-regulated ion channels and the cytoskeleton in astrocyte dysfunction in the white matter disease MLC Nicholas Mennona (College Park, MD, USA) Analyzing dynamics of calcium and actin in primary cortical rat astrocytes of differing cytoskeletal architectures Veronica Giusti (Padua, Italy) Unraveling novel players in astrocyte-mediated phagocytosis Linnéa Påvénius (Solna, Sweden) Mitochondrial dynamics in astrocytes Abel Eraso-Pichot (Bordeaux, France) Analysis of endocannabinoid dynamics in astrocytes Julianna Goenaga (Minneapolis, MN, USA) Estrogen signaling in nucleus accumbens astrocytes
  15:05-15:50	Frank Kirchhoff (University of Saarland • Homburg, Germany) Genetic and viral tools to sense and visualize glial activities [30 min + 10 min discussion]
  15:50-16:10	Coffee break
  16:10-16:55	Keith Murai (McGill University Health Centre • Montréal, QC, Canada) Embracing diversity: probing the molecular, structural, and functional heterogeneity of astrocytes [30 min + 10 min discussion]
  16:55-18:00	Student presentations [7 min + 3 min discussion each] Franziska Lechner (Neuherberg, Germany) The role of astroglial GLUT1 in the regulation of systemic glucose homeostasis Chloe Cable (Minneapolis, MN, USA) Glial modulation of electrical synapses in the retina Kelsea Gorzo (Calgary, Canada) Astrocyte mechanosensing regulates Ca2+ dynamics with metabolic and plasticity consequences for neurons Yael Morose (Jerusalem, Israel) Functional interactions between astrocytes and somatostatin neurons in the hippocampus Andrea Sánchez Ruiz (Madrid, Spain) Neuron-astrocyte communication in the dorsal raphe nucleus Michele Speggiorin (Padua, Italy) IP3R2-mediated astrocytic Ca2+ signaling in the Ventral Tegmental Area
  20:00	Dinner

• Tuesday, 5 April

  09:00-09:55	Student presentations [7 min + 3 min discussion each] Roberta Piovesana (Montreal, Canada) CB1 receptor antagonism alters Neuromuscular Junction re-innervation after nerve crush Andrés Baraibar Sierra (Leioa, Spain) Endocannabinoid mediated neuron-astrocyte communication in the cortex: implications in multiple sclerosis Tereza Filipi (Prague, Czech Republic) Glial pathology in the cortex of SOD1G93A mouse – a model of amyotrophic lateral sclerosis Viola Donati (Monterotondo, RM, Italy) In vivo study of astroglial connexins role on intercellular communication in a glioblastoma mouse model
  09:55-10:40	Gertrudis Perea (Cajal Institute CSIC • Madrid, Spain) Analysis of astrocytic impact beyond single synapses: modulation of neuronal networks [30 min + 10 min discussion]
  10:40-11:00	Coffee break
  11:00-11:55	Student presentations [7 min + 3 min discussion each] Jodie Man (Amsterdam, The Netherlands) Cortical grey matter pathology in vanishing white matter Melanie Huber (Neuherberg, Germany) A metabolic shift to lipid metabolism in hypothalamic astrocytes promotes weight gain on hypercaloric feeding Jose Noriega Prieto (Minneapolis, MN, USA) Calcium signaling in bergmann glia controls the intrinsic properties of purkinje cells in mouse model of spinocerebellar ataxia type 1 (SCA1) Sophie Schröder (Göttingen, Germany) The identification of a new lncRNA in astrocytes Mariana Sottomayor (Lisboa, Portugal) Cognitive deficits and astrocyte morphological changes in absence epilepsy
  11:55-12:40	Gian Michele Ratto (NEST - Scuola Normale Superiore • Pisa, Italy) In search of the unlikely: a statistical approach to calcium imaging and electrophysiology [30 min + 10 min discussion]
  12:40-14:10	Lunch
  14:10-15:05	Student presentations [7 min + 3 min discussion each] Réka Tóth (Szeged, Hungary) The role of endothelin-1 in the impairment of neurovascular coupling in a mouse model of ischemic stroke Parand Zarekiani (Amsterdam, The Netherlands) Pathology of the neurovascular unit in leukodystrophies: astrocytes as the common denominator? Leila Slaoui (Paris, France) Characterization of local translation in developing perivascular astrocytic processes Cecilia Zen (Rozzano, MI, Italy) Role of pentraxin3 in neurodevelopmental diseases Rachel Breton (Paris, France) A role for astrocytes in the visual cortex critical period
  15:05-15:50	Cristina García Cáceres (Helmholtz Zentrum München • Neuherberg, Germany) Exploring defects on the hypothalamic feeding circuits [30 min + 10 min discussion]
  15:50-18:00	Agora • Preparation (2) [with coffee]
  20:00	Pizza party

• Wednesday, 6 April

  9:00-9:45	Giovanni Marsicano (INSERM • Bordeaux, France) Behavioral analyses: data versus interpretations [30 min + 10 min discussion]
  9:45-10:30	Elly Hol (UMC Utrecht • Utrecht, The Netherlands) How to study human astrocytes: iPSC-models and omics [30 min + 10 min discussion]
  10:30-11:00	Coffee break
  11:00-11:45	Keith Murai (McGill University Health Centre • Montréal, QC, Canada) Astrocyte nanoarchitecture and function in the CNS [30 min + 10 min discussion]
  11:45-12:30	Frank Kirchhoff (University of Saarland • Homburg, Germany) The role of GABAB receptors in astrocytes [30 min + 10 min discussion]
  12:30-14:00	Lunch
  14:00	Departure for half-day outing

• Thursday, 7 April

  9:00-9:45	Amit Agarwal (Heidelberg University • Heidelberg, Germany) Glial Calcium dynamics in awake behaving mice [30 min + 10 min discussion]
  9:45-10:30	Gertrudis Perea (Cajal Institute CSIC • Madrid, Spain) GABAergic and astrocyte signaling interplay in prefrontal cortex improves decision-making [30 min + 10 min discussion]
  10:30-11:00	Coffee break
  11:00-11:45	Gian Michele Ratto (NEST - Scuola Normale Superiore • Pisa, Italy) When plasticity goes wrong: in vivo imaging of glioblastoma physiology [30 min + 10 min discussion]
  11:45-12:30	Alfonso Araque (University of Minnesota • Minneapolis, MN, USA) Scaling up tripartite synapses: from synapses to network and behavior [30 min + 10 min discussion]
  12:30-14:00	Lunch
  14:00-14:45	Giovanni Marsicano (INSERM • Bordeaux, France) CB1 receptors in astrocytes: quantity is not quality [30 min + 10 min discussion]
  14:45-18:00	Agora • Preparation (3) [with coffee]
  20:00	Dinner

• Friday, 8 April

  9:00-9:45	Cristina García Cáceres (Helmholtz Zentrum München • Neuherberg, Germany) Astrocyte-neuron crosstalk in metabolic control [30 min + 10 min discussion]
  9:45-10:30	Elly Hol (UMC Utrecht • Utrecht, The Netherlands) Functional consequences of reactive gliosis and their contribution to neurodegeneration [30 min + 10 min discussion]
  10:30-11:00	Coffee break
  11:00-11:45	Richard Robitaille (Université de Montréal • Montreal, QC, Canada) Glial cells at the neuromuscular junction as a therapeutic target in ALS [30 min + 10 min discussion]
  11:45-12:30	General Q&A session
  12:30-14:00	Lunch
  14:30-17:00	Agora presentations [with coffee]
  17:00-17:30	General discussion, Concluding Remarks, Questionnaires
  20:00	Farewell Dinner

• Saturday, 9 April

  Departure